Safety and antiviral effect of a triple combination of HIV-1 broadly neutralizing antibodies: a phase 1/2a trial

Nature Medicine 12 Sept 2024
DOI: 10.1038/s41591-024-03247-5

A chemogenetic screen reveals that Trpv1-expressing neurons control regulatory T cells in the gut

Science: 2 August 2024
DOI: 10.1126/science.adk1679

A metabolic switch orchestrated by IL-18 and the cyclic dinucleotide cGAMP programs intestinal tolerance

Immunity 20 June 2024
DOI: 10.1016/j.immuni.2024.06.001

Affinity gaps among B cells in germinal centers drive the selection of MPER precursors

Nature 30 May 2024
DOI: 10.1038/s41590-024-01844-7

mRNA-LNP HIV-1 trimer boosters elicit precursors to broad neutralizing antibodies

Science 17 May 2024
doi: 10.1126/science.adk0582

mRNA-LNP prime boost evolves precursors toward VRC01-like broadly neutralizing antibodies in preclinical humanized mouse models

Science Immunology 16 May 2024
DOI: 10.1126/sciimmunol.adn0622

Charting the cellular biogeography in colitis reveals fibroblast trajectories and coordinated spatial remodeling

Cell 11 April 2024
DOI: 10.1016/j.cell.2024.03.013

Comparison of the immunogenicity and protective efficacy of ACAM2000, MVA, and vectored subunit vaccines for Mpox in rhesus macaques

Science Translational Medicine 27 March 2024
DOI: 10.1126/scitranslmed.adl4317

AIRE relies on Z-DNA to flag gene targets for thymic T cell tolerization

Nature 13 March 2024
DOI: 10.1038/s41586-024-07169-7