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Welcome to the HMS Department of Immunology

We are a highly collaborative group of scientists from across the Harvard community including the Ragon Institute, Broad Institute, and Harvard Stem Cell Institute, working to understand the mechanisms and applications of immunity and immunobiology. Our research covers the spectrum of immunology, from basic science to translation into human biology and disease prevention and treatment. Here you'll find our faculty, community events, and resources available to our affiliates.


Are you looking for the Immunology PhD Program? Check here!

Junior Faculty Collaborations Strengthen Science

In the news...

Illustration of bacteria under microscope: Leila_Divine/Getty Images Plus

The Long Game of Microbiome Science

Looking beyond the hype, three experts explain what research on the gut microbiome might actually deliver.

Harvard Medical News

Daisy Hoagland (left) and Ruth Franklin. Photos by Niles Singer/Harvard Staff Photographer

Your body fought off the virus — but damaged your lungs

Ruth Franklin's lab zeroes in on potential key to rapidly repairing tissue harmed by inflammation

Harvard Gazette

Arlene Sharpe and Gordon Freeman accept their Gretner-Thurlemann Prize

Gordon Freeman, Arlene Sharpe Receive Inaugural Gretener-Thürlemann Prize

The prize recognizes outstanding researchers in medicine, chemistry and physics for foundational and pioneering research of societal benefit. 

Harvard Medical News

Ruaidhri Jackson

Ruaidhrí Jackson named ICIS New Investigator Awardee

Congratulations, Ruaidhrí!

International Cytokine and Interferon Society

Arlene and Gordon at home

The Long Journey of Gordon Freeman and Arlene Sharpe

The two immunologists have shared a lifetime of scientific exploration and discovery

Harvard Medical News

Arlene Sharpe and Gordon Freeman in lab

He had six months to live. Then came an experimental cancer treatment launched by Harvard researchers.

Before her federal funding was cut, Dr. Arlene Sharpe and colleagues paved the way for immunotherapy treatments.

Boston Globe

Recent publications

CBDM Lab

Irisin ameliorates obesity and insulin resistance via adipose tissue IL-33 and regulatory T cells

Nature Metabolism 3 April 2026
DOI: 10.1038/s42255-026-01491-2

Agudo Lab

A glucocorticoid–FAS axis controls immune evasion during metastatic seeding

Nature 4 Mar 2026
DOI: 10.1038/s41586-026-10222-2

CBDM Lab

Piezo1-dependent activation of stromal cells ignites muscle inflammation in exercise and injury and is associated with inflammaging

Nature Immunology 2 Mar 2026
DOI: 0.1038/s41590-026-02435-4

CBDM Lab

Regulatory T cells safeguard liver health during metabolic-associated steatohepatitis

Proc Natl Acad Sci 16 Feb 2026
DOI: 10.1073/pnas.2536314123

Wucherpfennig Lab

Persistent T cell activation and cytotoxicity against glioblastoma following single oncolytic virus treatment in a clinical trial.

Cell 11 Feb 2026
DOI: 10.1016/j.cell.2025.12.055

More

Header image credits (left to right):

  • A fluorescent micrograph of the hippocampal region of the brain of an Alzheimer's disease transgenic mouse by Jinsu Park, 2024, Huh Lab;
  • Whole mount image of mouse intestine stained for neurons by Ademi Zhakyp 2023, von Andrian Lab;
  • Fluorescent micrograft of T effector cells in endothelial microvessels. Olga Barreiro 2025, von Andrian Lab.
Harvard Medical School
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Department of Immunology

77 Avenue Louis Pasteur, NRB 1030
Boston, MA 02115
P: (617) 432-6569
F: (617) 432-6570

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