The Department houses the core team of the NIAID-supported Immunological Genome Project, an international consortium of Immunologists and Computational Biologists who aim to chart, in a comprehensive but detailed manner, the patterns and regulatory networks of gene expression in the mouse immune system.  The project encompasses the innate and adaptive immune systems, surveying all cell types of the myeloid and lymphoid through differentiation, tissue localization, pathogen challenges and genetic variation. Various genomic technologies for profiling and chromatin analysis are used, and computational machine-learning is applied to decipher regulatory networks.

ImmGen is a public resource, and its data are publicly accessible through dedicated databrowsers at ImmGen.org, or through smartphones supports (ImmGen iPhone and Android apps)